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Rilmenidine decreases the oleic acid-induced lipid accumulation in Hep G2 cells. Rilmenidine activates I-1 receptor to increase intracellular calcium ions that may enhance the phosphorylation of p38 to higher the expression of FXR for improvement of hepatic steatosis in both animals and cells.
| Molecular Weight | 278.24 |
| Formula | C10H19N2O5P |
| CAS Number | 85409-38-7 |
| Form | Solid |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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