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Rezivertinib

Cat. No. M45386

All AbMole products are for research use only, cannot be used for human consumption.

Rezivertinib Structure
Synonym:

BPI-7711

Price and Availability

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Quality Control & Documentation
Biological Activity

Rezivertinib is an orally effective, highly selective and irreversible third-generation EGFR tyrosine kinase inhibitor (TKI) with high potency against common activating EGFR and resistant T790M mutations.Rezivertinib exhibits excellent CNS penetration and antitumor activity.

Chemical Information
Molecular Weight 486.57
Formula C27H30N6O3
CAS Number 1835667-12-3
Form Solid
Solubility (25°C) DMSO >100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sally C M Lau, et al. J Thorac Oncol. And Still They Come Over Troubled Waters: Can Asia's Third-Generation EGFR Tyrosine Kinase Inhibitors (Furmonertinib, Aumolertinib, Rezivertinib, Limertinib, Befotertinib, SH-1028, and Lazertinib) Affect Global Treatment of EGFR+ NSCLC

[2] Misako Nagasaka, et al. J Thorac Oncol. Beyond Osimertinib: The Development of Third-Generation EGFR Tyrosine Kinase Inhibitors For Advanced EGFR+ NSCLC

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  Catalog
Abmole Inhibitor Catalog




Keywords: Rezivertinib, BPI-7711 supplier, EGFR/HER2, inhibitors, activators

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