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Retinoic acid is A metabolite of vitamin A and plays an important role in cell growth, differentiation and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors with an IC50 of 14 nM for RARα/β/γ. The Kd value of Retinoic acid combined with PPARβ/δ is 17 nM. Retinoic acid inhibits the transcription factor Nrf2 by activating Retinoic acid receptors.
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AhR/ROS-mediated endoplasmic reticulum stress contributes to PFOSA-induced cardiac defects.
Retinoic acid purchased from AbMole
Cell Death Differ. 2023 Mar 9.
Targeting HDAC3 to overcome the resistance to ATRA or arsenic in acute promyelocytic leukemia through ubiquitination and degradation of PML-RARα
Retinoic acid purchased from AbMole
| Molecular Weight | 300.44 |
| Formula | C20H28O2 |
| CAS Number | 302-79-4 |
| Solubility (25°C) | DMSO 45 mg/mL (ultrasonic and warming) |
| Storage | -20°C, protect from light, dry, sealed |
[1] Samarawickrama C, et al. Surv Ophthalmol. Retinoic acid and the ocular surface.
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Products are for research use only. Not for human use. We do not sell to patients.
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