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Rencofilstat

Cat. No. M31399

All AbMole products are for research use only, cannot be used for human consumption.

Rencofilstat Structure
Synonym:

RCF; CRV431

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Quality Control & Documentation
Biological Activity

Rencofilstat (CRV431) is a cyclosporine derivative as well as an orally active cycloheximide (CYPA) inhibitor for studies related to non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma.

Chemical Information
Molecular Weight 1303.76
Formula C67H122N12O13
CAS Number 1383420-08-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Stephen A Harrison, et al. Hepatol Commun. Rencofilstat, a cyclophilin inhibitor: A phase 2a, multicenter, single-blind, placebo-controlled study in F2/F3 NASH

[2] Ellen Remenchik, et al. Clin Pharmacol Drug Dev. Effect of a High-Fat Meal on Single-Dose Rencofilstat (CRV431) Oral Bioavailability in Healthy Human Subjects

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Keywords: Rencofilstat, RCF; CRV431 supplier, Cyclophilin, inhibitors, activators

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