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Relamorelin (RM-131), a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a Ki of 0.42 nM for GHS-1a receptor. Relamorelin is centrally penetrant. Relamorelin increases growth hormone levels and accelerates gastric emptying. Relamorelin has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research.
| Molecular Weight | 790.97 |
| Formula | C43H50N8O5S |
| CAS Number | 661472-41-9 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Madhusudan Grover, et al. Gut. Gastroparesis: a turning point in understanding and treatment
| Related Ghrelin Receptor/GHSR Products |
|---|
| Anamorelin
Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. |
| Ibutamoren mesylate
Ibutamoren (MK 0677) mesylate is a high affinity ghrelin receptor agonist. |
| Capromorelin tartrate
Capromorelin tartrate is a potent ghrelin receptor agonist/growth hormone secretagogue (Ki = 7 nM). |
| JMV 2959
JMV 2959 is a growth hormone secretin receptor type 1A (GHS-R1A) antagonist that acts on LC-PK1 cells and inhibits GHS-R1A with an IC50 value of 32±3 nM. |
| Anamorelin hydrochloride
Anamorelin (RC-1291) hydrochloride is a potent ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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