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Relamorelin acetate

Cat. No. M28907

All AbMole products are for research use only, cannot be used for human consumption.

Relamorelin acetate Structure
Synonym:

RM-131 acetate; BIM-28131 acetate

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Quality Control & Documentation
Biological Activity

Relamorelin (RM-131) acetate, a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a Ki of 0.42 nM for GHS-1a receptor. Relamorelin acetate is centrally penetrant. Relamorelin acetate increases growth hormone levels and accelerates gastric emptying. Relamorelin acetate has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research.

Chemical Information
Molecular Weight 851.02
Formula C45H54N8O7S
CAS Number 1809080-14-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Angelika Fretzen. Bioorg Med Chem. Peptide therapeutics for the treatment of gastrointestinal disorders

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Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM.

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Ibutamoren (MK 0677) mesylate is a high affinity ghrelin receptor agonist.

Capromorelin tartrate

Capromorelin tartrate is a potent ghrelin receptor agonist/growth hormone secretagogue (Ki = 7 nM).

JMV 2959

JMV 2959 is a growth hormone secretin receptor type 1A (GHS-R1A) antagonist that acts on LC-PK1 cells and inhibits GHS-R1A with an IC50 value of 32±3 nM.

Anamorelin hydrochloride

Anamorelin (RC-1291) hydrochloride is a potent ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay.

  Catalog
Abmole Inhibitor Catalog




Keywords: Relamorelin acetate, RM-131 acetate; BIM-28131 acetate supplier, Ghrelin Receptor/GHSR, inhibitors, activators

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