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Relacorilant

Cat. No. M11555

All AbMole products are for research use only, cannot be used for human consumption.

Relacorilant Structure
Synonym:

CORT 125134

Size Price Availability Quantity
1mg USD 80 In stock
5mg USD 200 In stock
10mg USD 330 In stock
25mg USD 660 In stock
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Quality Control & Documentation
Biological Activity

Relacorilant is a selective, oral bioeffective glucocorticoid receptor antagonist (Ki of 7.2 nM in HepG2 TAT assay and 12,81.2 nM in rat, human and monkey glucocorticoid receptor in cell-based assay). Relacorilant can be used in studies of Cushing's syndrome.

Chemical Information
Molecular Weight 586.56
Formula C27H22F4N6O3S
CAS Number 1496510-51-0
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Andrew E Greenstein, et al. Oncotarget. Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells

[2] Joseph M Custodio, et al. J Clin Pharmacol. An In Vitro and In Vivo Evaluation of the Effect of Relacorilant on the Activity of Cytochrome P450 Drug Metabolizing Enzymes

[3] Richard A Feelders, et al. Lancet Diabetes Endocrinol. Advances in the medical treatment of Cushing's syndrome

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