Free shipping on all orders over $ 500

Refanezumab

Cat. No. M24583

All AbMole products are for research use only, cannot be used for human consumption.

Refanezumab Structure
Synonym:

GSK249320

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Refanezumab (GSK249320) is an IgG1-type humanized monoclonal antibody directed against myelin-associated glycoprotein (MAG). Refanezumab binds to MAG and blocks MAG-mediated inhibition of axonal regeneration. Refanezumab can cross the blood-brain barrier (BBB) in animal stroke models. Refanezumab has the potential for the enhancement of recovery of function poststroke.

Chemical Information
CAS Number 1233953-61-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Scott Barbay, et al. Stroke. Effects of postinfarct myelin-associated glycoprotein antibody treatment on motor recovery and motor map plasticity in squirrel monkeys

[2] B Abila, et al. Clin Pharmacol Ther. First-time-in-human study with GSK249320, a myelin-associated glycoprotein inhibitor, in healthy volunteers

Related Products
Lactate calcium

Lactate calcium is an excellent calcium fortifier that works better than inorganic calcium. Lactate calcium is used as an antacid.

Coniferyl ferulate

Coniferyl ferulate is a potent glutathione S-transferase (GST) inhibitor that reverses multidrug resistance and down-regulates p-glycoprotein. Coniferyl ferulate strongly inhibited human placental glutathione S-transferase with IC50 of 0.3 μM.

NXY-059

NXY-059 is a free radical-trapping neuroprotectant that has been reported to reduce infarct size and preserve brain function in experimental models of acute ischemic stroke.

Tie2 kinase inhibitor

Tie2 kinase inhibitor is a potent, reversible, and ATP-binding site-targeting Tie2 inhibitor with an IC50 of 250 nM.

Calcium levofolinate

Calcium levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.

  Catalog
Abmole Inhibitor Catalog




Keywords: Refanezumab, GSK249320 supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.