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Genus: Rat
Expression system: E.coli
Purity: >95% as determined by reduced SDS-PAGE
Endotoxin: less than 0.1 ng/µg (1 EU/µg) by LAL test
Molecular weight; 11.3 KDa
Storage and Stability: Lyophilized proteins should be stored at <-20°C, although stable at room temperature for 3 weeks. Reconstituted protein solutions can be stored at 4-7°C for 2-7 days. Recombinant sample aliquots are stable for 3 months at <-20°C.
Bioactivity: Protein S100-A8 (Mrp8) contains 2 EF-hand structural domains and belongs to the S-100 family. mrp8 binds two calcium ions per molecule and has an affinity similar to that of S-100 proteins. s100 proteins are localized in the cytoplasm and/or nucleus of a variety of cells and are involved in regulating a number of cellular processes, such as cell cycle progression and differentiation. the S100 gene includes at least 13 members, which are located as a cluster on chromosome 1q21. It may function as an inhibitor of casein kinase and as a cytokine. Altered expression of this protein has been associated with cystic fibrosis disease.
| Solubility (25°C) | It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] H Y Sroussi, et al. J Dent Res. S100A8 triggers oxidation-sensitive repulsion of neutrophils
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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