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Recombinant Rat IL-4 Protein is a multidirectional cytokine that regulates various T cell and B cell responses such as cell proliferation, survival, and gene expression. IL-4 is produced by mast cells, T cells and bone marrow stromal cells, and regulates the differentiation of naive CD4+ T cells into helper Th2 cells. Its cytokine secretion features include secretion of IL-4, IL-5, IL-6, and IL- 10 and IL-13, are conducive to humoral immune response. The other main function of IL-4 is to regulate the conversion of immunoglobulins into IgG 1 and IgE subtypes.
Depends on its ability to stimulate the proliferation of TF-1 cells, the expected ED50 is 200~400 ng/ml.
Expression host is Human HEK293 cells
| Solubility (25°C) | Water Saline PBS |
| Storage | 2-8°C, dry, sealed |
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