All AbMole products are for research use only, cannot be used for human consumption.
Interleukin-4 (IL-4) is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. IL-4 regulates the differentiation of native CD4+ T cells (Th0 cells) into helper Th2 cells, and regulates the immunoglobulin class switching to the IgG1 and IgE isotypes. Interleukin-4 is produced by mast cells, T cells, and bone marrow stromal cells. It is a key regulator in hormone control and adaptive immunity. IL-4 also plays a major role in inflammation response and wound repair via activation of macrophage into M2 cells.
Measured in a proliferationassay using C6 cells, the ED50 is < 0.2 μg/ml.
Accession: P20096
Apparent Molecular Weight: 18~22 kDa, reducing conditions
Endotoxin < 0.2 EU/μg
Lyophilized after extensive dialysis against PBS.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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