All AbMole products are for research use only, cannot be used for human consumption.
TNF-α (HEK293) is a pleiotropic pro-inflammatory cytokine secreted by a variety of cells such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts. TNF-α is cytotoxic to a variety of tumor cells and is an important factor that mediates the immune response to bacterial infections. TNF-α also plays a role in the induction of septic shock, autoimmune diseases, rheumatoid arthritis, inflammation and diabetes.
Measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells, the ED50 is < 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 107 units/mg.
Accession: P06804
Apparent Molecular Weight: ~17.3 kDa, under reducing conditions
Endotoxin < 0.2 EU/μg
Lyophilized after extensive dialysis against PBS.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
| Storage | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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