All AbMole products are for research use only, cannot be used for human consumption.
Species: Mouse/Rat
Expression system: Mammalian
Purity: > 95% as determined by reduced SDS-PAGE
Endotoxin: less than 0.001 ng/µg (0.01 EU/µg)
Molecular weight: 12.8 KDa
Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
Storage and stability: The freeze-dried protein should be stored at ≤-20℃ and stored stably for one year after receiving. The recombinant protein solution can be stored at 2-8℃ for 2-7 days. The recombinant samples were stabilized at ≤-20°C for 3 months.Measured by its ability to inhibit IL-4-dependent proliferation of TF‑1 human erythroleukemic cells, the ED50 for this effect is 5-25 pg/ml.
Biological activity: Transforming growth factor β1 (TGFβ1) is the prototype of the growth superfamily of peptide growth factors, which plays an important role in a variety of cellular processes including cell cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing and immune monitoring. TGF-β1, TGF-β2, and TGF-β3 signals are transmitted through the same heteromer receptor complex consisting of ligands that bind to TGF-βreceptor type II (TβR-II) and TGF-βI (TβR-I). Signal transduction from receptor to nucleus is mediated by SMADs. TGF-β is expressed in cartilage, bone, teeth, muscle, heart, blood vessels, hematopoietic cells, lungs, kidneys, intestines, liver, eyes, ears, skin and nervous system.
Biol Pharm Bull. 2024 Oct 30;47(10):1774-1785.
5-Demethylnobiletin Ameliorates Isoproterenol-Induced Cardiac Fibrosis and Apoptosis by Repressing the Sirt1/FOXO3a/NF-κB and Wnt/β-Catenin Pathways
Recombinant Mouse/Rat TGF-beta 1 (HEK293) purchased from AbMole
| Solubility (25°C) | Dissolve the lyophilized protein in 4mM HCl. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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