All AbMole products are for research use only, cannot be used for human consumption.
RANKL is a member of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. Tnfsf11 is involved in many fundamental biological processes, such as acting as a regulator of interactions between T cells and dendritic cells, regulating T cell-dependent immune responses and enhancing bone resorption in malignant humoral hypercalcemia. It enhances the ability of dendritic cells to stimulate the proliferation of naive T cells.
Recombinant Mouse RANKL (E. coli) expressed the target gene encoding Pro143-Asp316.
Determined by its dose-dependent ability to induce reporter gene in HT-29 NF-κB Luc reporter cells, the ED50 for this effect is 0.5-2 ng/ml.
Accession: O35235
Endotoxin < 0.01 EU/µg
Approximately Molecular Weight: 19.4kDa, a single non-glycosylated polypeptide chain containing 174 amino acids
Lyophilized from a 0.2µm filtered concentrated solution in 20mMPB, 300mM NaCl, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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