All AbMole products are for research use only, cannot be used for human consumption.
Species: Mouse
Expression system: HEK 293
Purity: SDS-PAGE analysis > 95%, HPLC analysis > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: 10~ 40kda, sds-page under reduction conditions
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.
Bioactivity: ED50 < 0.4 ng/ mL, cell proliferation assay was performed using NIH-3T3 cells. In vivo, OSM is secreted by activated T cells, monocytes, neutrophils, and endothelial cells. OSM is related to LIF and shares a receptor with LIF. Human OSM can bind to GP130 and recruit OSM receptor β or LIF receptor β to form ternary complexes. OSM stimulates the growth of different cell types, including megakaryocytes, fibroblasts, vascular endothelial cells, and T cells. OSM inhibits the proliferation of several cancer cell lines, such as solid tissue tumor cells, lung cancer cells, melanoma cells, and breast cancer cells.
| Solubility (25°C) | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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