All AbMole products are for research use only, cannot be used for human consumption.
Lipocalin-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), is a secreted protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that allows it to be secreted and form a complex with matrix metalloproteinase-9 (MMP-9) via a disulfide bond. Similar to other members of the lipocalin family, Lipocalin-2 is involved in different cellular processes, including transport of small hydrophobic molecules, protection of MMP-9 from protease degradation, and cellular signaling. In addition, Lipocalin-2 can bind tightly to bacterial iron via cell surface receptors and may be an effective bactericidal agent by sequestering iron, regulating innate immunity and protecting renal epithelial cells from ischemia-reperfusion injury. The protein is expressed mainly in neutrophils and at lower levels in epithelial cells of the kidney, prostate, respiratory and digestive tracts.
The target gene encoding Gln21-Asn200 was expressed with a C-terminal polyhistidine tag.
Accession: P11672
APMol Mass: 20-28 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM Histidine-HCl, 8% Trehalose, 2% Glycine, 50mM NaCl, 0.05% Tween 80, pH6.5.
| Form | Lyophilized powder |
| Solubility (25°C) | Dissolve the lyophilized protein in distilled water. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at ≤ -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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