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Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity.
Recombinant Mouse Matrix Metalloproteinase 12 (MMP12) expressed the target gene encoding Ala29-Cys473 with a 6His tag at the C-terminus. The proenzyme needs to be activated by APMA for an activated form.
Accession: P34960
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 64 KDa, reducing conditions
Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, 0.01%Tween80, 1mM EDTA, 50% Glycerol, pH6.0.
The product is shipped on dry ice. Upon receipt, store it immediately at the temperature listed below.
| Form | Solution |
| Storage | Store at ≤ -70°C, stable for 6 months after receipt. |
| Related Enzymes & Regulators Products |
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MAPK8 is a multifunctional serine/threonine protein kinase that complexly regulates multiple cellular processes, including cell proliferation, apoptosis, and differentiation. MAPK8 is activated by MAP2K4/MKK4 and MAP2K7/MKK7, phosphorylates AP-1 components, and affects transcriptional activity. |
| Recombinant Human MMP-9 (HEK293, C-6His)
Recombinant human matrix metalloproteinase-9 is produced by a mammalian expression system and the target gene encoding Ala19-Asp707 has a 6His tag at the C-terminus. The proenzyme needs to be activated by APMA to form the active form. Protein ID: AAH06093.1. |
| Recombinant Human MMP-3 (HEK293, C-6His)
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes. Recombinant Human Matrix Metalloproteinase-3 is produced by Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by Chymotrypsin for an activated form. |
| Recombinant Human MMP-1 (HEK293, C-6His)
Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens. The target gene encoding Phe20-Asn469 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA for an activated form. |
| Recombinant Human MMP-2 Protein (HEK293, C-6His)
Recombinant Human MMP-2 (also known as matrix metalloproteinase-2) is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. MMP-2 can act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. The proenzyme needs to be activated by APMA for an activated form. |
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Products are for research use only. Not for human use. We do not sell to patients.
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