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Mouse Lactate dehydrogenase A (LDHA) is a member of the LDH/MDH superfamily and LDH family. LDHA can promote the Warburg effect to produce lactate and Adenosine Triphosphate (ATP) in aerobic conditions. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours. LDHA plays an important role in the development, invasion and metastasis of malignancies. LDHA catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+.
Recombinant Mouse LDHA expressed the target gene encoding Met1-Phe332 with a 6His tag at the C-terminus.
Measured by its ability to reduce pyruvate to lactate, the specific activity is >50,000 pmoles/min/μg.
Accession: P06151
Apparent Molecular Weight: 37 KDa, under reducing conditions
Endotoxin < 1 EU/µg
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50%Glycerol, 500 mMNaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween80, 1mM EDTA, pH 9.0.
The product is shipped on dry ice packs. Upon receipt, store it immediately at the temperature listed below.
| Form | Solution |
| Storage | Store at ≤ -20°C, stable for 12 months after receipt. Please minimize freeze-thaw cycles. |
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Products are for research use only. Not for human use. We do not sell to patients.
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