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Recombinant Mouse IL-36 beta (E.coli)

Cat. No. M13444

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse IL-36 beta (E.coli) Structure
Synonym:

IL-36 beta (E.coli)

Size Price Availability Quantity
10ug USD 140 In stock
50ug USD 365 In stock
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Quality Control & Documentation
  • Purity: >95% , Endotoxin < 1 EU/ug
  • COA
  • MSDS
Biological Activity

Species: Mouse
Purity: > 95% as determined by reduced SDS-PAGE
Endotoxin: less than 0.1 ng/ug (1 EU/ug) as tested by LAL
Redissolve: centrifuge the tube before opening it. Do not mix by eddy current or pipette. Recombination to concentrations below 100 μg/ mL is not recommended. Lyophilized egg whites are dissolved in distilled water. Separate the reformulated solution to reduce freeze-thaw cycles.
Storage and stability: Lyophilized proteins should be stored at < -20°C but can be stored at room temperature for up to 3 weeks. The recombinant protein solution can be stored at 4-7℃ for 2-7 days. The isometric solution of the recombinant sample was stable at < -20°C for 3 months.


Biological activity: IL-36B is synthesized in a variety of cells, including resting and active monocytes and B cells. The receptor for IL-36 β is thought to bind IL-1 Rrp2 and IL-1 RAcP. Interleukin 36 β is a part of the IL-36 signaling system and is believed to exist in the epithelial barrier and participate in local inflammatory responses. Similar to the IL-1 system, it is shared with the coreceptor IL1RAP. In addition, interleukin 36 β may be involved in skin inflammation, act on keratinocytes, dendritic cells, and indirectly on T cells, promoting tissue infiltration, cell maturation, and cell proliferation. T promoter 1 (Th1) cells, cultured CD4+ T cells, and spleen cells stimulate the surface expression of CD80, CD86, and MHC class II, and induce the production of IFN - γ, IL-4, and IL-17, which play an important role in dendritic cell maturation.

Chemical Information
Solubility (25°C) It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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Keywords: Recombinant Mouse IL-36 beta (E.coli), IL-36 beta (E.coli) supplier, Cytokines and Growth Factors, inhibitors, activators

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