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Recombinant Mouse IL-17A (CHO)

Cat. No. M15033

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse IL-17A (CHO) Structure
Synonym:

IL17A, CTLA-8

Size Price Availability Quantity
10ug USD 175 In stock
50ug USD 360 In stock
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Quality Control & Documentation
  • Purity: >95% , Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Species: Mouse
Expression system: CHO
Purity: SDS-PAGE, > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: 15~ 22kda, sds-page under reduction conditions
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.


Biological activity: Interleukin-17A (also known as CTLA-8) is a pleiotropic cytokine expressed by T cells with a high degree of homology to the protein encoded by the ORF13 gene of herpes virus squirrel monkey. CDNA clones encoding IL-17 have been isolated from activated rat, mouse, and human T cells. Il-17 represents a structurally related family of cytokines that share a highly conserved C-terminal region but differ from each other in their N-terminal regions and their unique biological roles. The six known members of the family, IL-17A through IL-17F, are secreted as homologous dimers.

Chemical Information
Solubility (25°C) It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lei Han, et al. Front Immunol. A Novel Bifunctional Fusion Protein, Vunakizumab-IL22, for Protection Against Pulmonary Immune Injury Caused by Influenza Virus

[2] Yunxin Wang, et al. Biomed Pharmacother. A recombinant IgG-like bispecific antibody acting as interleukin-1β and interleukin-17A inhibitor exhibits a promising efficacy for rheumatoid arthritis

[3] Shinya Hatano, et al. Vaccine. Recombinant Mycobacterium bovis bacillus Calmette-Guérin expressing Ag85B-IL-7 fusion protein enhances IL-17A-producing innate γδ T cells

[4] Seon-Yeong Lee, et al. J Immunol. IL-12p40 Homodimer Ameliorates Experimental Autoimmune Arthritis

[5] Shen-An Hwang, et al. Innate Immun. Effects of CHO-expressed recombinant lactoferrins on mouse dendritic cell presentation and function

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Keywords: Recombinant Mouse IL-17A (CHO), IL17A, CTLA-8 supplier, Cytokines and Growth Factors, inhibitors, activators

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