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Recombinant Mouse IL-13 Protein is an immunoregulatory cytokine belonging to the IL-4/IL-13 family, a multifunctional cytokine whose main role is to reduce the inflammatory response. IL-13 signals through a receptor complex composed of IL-4Rα and IL13Rα1 (or IL13Rα2). IL-13 inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α and IL-6 by monocytes and macrophages. It also induces B cell activation and IgE secretion.
Recombinant Mouse IL-13 Protein expressed the target gene encoding Pro22-Phe131 with a polyhistidine tag at the C-terminus.
Measured in a cell proliferation assay using R&D TF-1 cells, the ED50 is < 20.0 ng /ml.
Accession: P20109
Endotoxin < 0.2 EU/µg
Apparent Molecular Weight: 14~30 kDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[4] Akiko Suzuki, et al. Cytokine. Targeting of IL-4 and IL-13 receptors for cancer therapy
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