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Recombinant Mouse HGF (HEK293,C-6His)

Cat. No. M15076

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse HGF (HEK293,C-6His) Structure
Synonym:

Hepatopoietin-A;Scatter factor;SF;deafness, autosomal recessive 39

Size Price Availability Quantity
10ug USD 260 In stock
50ug USD 780 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.01 EU/μg
  • COA
  • MSDS
Biological Activity

Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. 

Recombinant Mouse Hepatocyte Growth Factor expressed the target gene encoding Gln33-­Leu728 with a 6His tag at the C-terminus.


Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Sotaro Motoi, et al. Int J Mol Sci. Serum APOA4 Pharmacodynamically Represents Administered Recombinant Human Hepatocyte Growth Factor (E3112)

[2] Chiara Modica, et al. J Exp Clin Cancer Res. A receptor-antibody hybrid hampering MET-driven metastatic spread

[3] Szu-Ying Chu, et al. Nat Commun. Mechanical stretch induces hair regeneration through the alternative activation of macrophages

[4] Kyeong Ryang Ko, et al. Biochem Biophys Res Commun. c-Fos is necessary for HGF-mediated gene regulation and cell migration in Schwann cells

[5] Katsuya Sakai, et al. J Biochem. Hepatocyte growth factor and Met in drug discovery

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Keywords: Recombinant Mouse HGF (HEK293,C-6His), Hepatopoietin-A;Scatter factor;SF;deafness, autosomal recessive 39 supplier, Cytokines and Growth Factors, inhibitors, activators

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