All AbMole products are for research use only, cannot be used for human consumption.
Heparin-binding EGF-like growth factor (HB-EGF) is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein. It has been shown to play a role in wound healing, cardiac hypertrophy and heart development and function. The transmembrane form of HB-EGF is the unique receptor for diptheria toxin and functions in juxtacrine signaling in cells. HB-EGF can bind two locations on cell surfaces, heparan sulfate proteoglycans and EGF-receptor effecting cell to cell interactions.
Recombinant Mouse HB-EGF expressed the target gene encoding Asp63-Leu148.
Determined by a cell proliferation assay using murine Balb/c 3T3 cells, the ED50 is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg.
Accession: Q06186
Theoretical Molecular Weight: 9.8 kDa
Endotoxin < 1 EU/µg
Lyophilized from a 0.2 μm filtered concentrated solution in 10 mM PB, 150 mM NaCl, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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