All AbMole products are for research use only, cannot be used for human consumption.
Granzyme B (GZMB) is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Recombinant Mouse Granzyme B expressed the target gene encoding Gly19-Ser247 with a 6His tag at the C-terminus.
Accession: P04187
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 35 KDa, reducing conditions
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
The product is shipped on dry ice packs. Upon receipt, store it immediately at the temperature listed below.
| Form | Solution |
| Storage | Store at ≤ -70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| Related Cytokines and Growth Factors Products |
|---|
| Recombinant Human CD48/SLAMF2 (HEK293,C-Fc-6His)
Recombinant human CD48/SLAMF2 protein plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma. |
| Recombinant Human IFNγ (CHO)
Human Interferon gamma (hIFN-γ) (CHO) is a dimerized soluble cytokine that is the only member of the type II class of interferons. |
| Recombinant Human EPO Protein (CHO)
Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. |
| Recombinant Human GM-CSF (HEK293, C-His)
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor is a hematopoietic growth factor and immune modulator. |
| Recombinant Human IL-1α Protein (E. coli)
Interleukin 1 (IL-1) is a peptide with a molecular mass of 17 kd and two isoforms, IL-1α and IL-1β. IL-1ɑ consists of 159 amino acids. Measured by its ability to induce interferon γ secretion from human natural killer lymphoma NK-92 cells, the ED50 of this effect is ≤100 ng/mL. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
