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Fas Ligand is the ligand for FAS, it is a transmembrane protein which binds to TNFRSF6/FAS. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
The recombinant mouse Fas Ligand consists of 158 amino acids and predicts a molecular mass of 18.2 kDa. A DNA sequence encoding the mouse Fas Ligand (Pro132-Leu279) was expressed with a polyhistidine tag at the N-terminus.
Endotoxin < 1 EU/µg
Lyophilized from sterile PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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