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Recombinant Mouse CT-1 (HEK 293)

Cat. No. M15029

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse CT-1 (HEK 293) Structure
Synonym:

CTF1; CT-1

Size Price Availability Quantity
10ug USD 230 In stock
50ug USD 640 In stock
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Quality Control & Documentation
  • Purity: >95% , Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Species: Mouse
Expression system: HEK 293
Purity: SDS-PAGE, > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: 22~ 27kda, sds-page under reduction conditions
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.


Biological activity: EC50 value of cardiac trophic factor-1 ≤1.25 ng/ mL and specific activity ≥0.8 × 106 units /mg were determined by dose-dependent proliferation of TF-1 cells. Ct-1 is associated with the pathophysiology of various heart diseases such as hypertension, myocardial infarction, valvular heart disease and congestive heart failure. This protein exerts its cellular effects by interacting with a glycoprotein 130 (GP130)/ leukemic suppressor receptor β (LIFR) heterodimer. Ct-1 activates cardiomyocyte phosphatidylinositol 3 kinase (PI-3 kinase) and enhances transcription factor NF-κB DNA-binding activity. Ct-1 is highly expressed in the heart, skeletal muscle, prostate and ovary, and low in lung, kidney, pancreas, thymus, testis and small intestine.

Chemical Information
Solubility (25°C) It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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Keywords: Recombinant Mouse CT-1 (HEK 293), CTF1; CT-1 supplier, Cytokines and Growth Factors, inhibitors, activators

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