All AbMole products are for research use only, cannot be used for human consumption.
Recombinant Human TGF-β2 Protein is a multifunctional cytokine that regulates cell proliferation, growth, differentiation and movement, as well as the synthesis and deposition of extracellular matrix. The three mammalian subtypes, transforming growth factor-β, transforming growth factor-β1, β2, and β3, send signals through the same receptor, causing similar biological responses. TGF-β2 has an inhibitory effect on IL-2-dependent T cell growth, and may exert an autocrine function through immune surveillance that inhibits tumor growth.
Measured in a cell proliferation assay using mouse HT-2 cells, the ED50 is < 0.2 ng/ml.
Expression host is Human Cells
Accession: P61812
Endotoxin < 1 EU/µg
Apparent Molecular Weight: ~12.7 kDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution in 4 mM HCl.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[3] Johannes Gottanka, et al. Invest Ophthalmol Vis Sci. Effects of TGF-beta2 in perfused human eyes
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Products are for research use only. Not for human use. We do not sell to patients.
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