All AbMole products are for research use only, cannot be used for human consumption.
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF-1 binds primarily to CXC receptor 4 (CXCR4; CD184). The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription. SDF-1/CXCL12 has crucial roles in the formation of multiple organ systems during embryogenesis and in the regulation of bone marrow haematopoiesis and immune function in the postnatal organism.
MVSLSYRCPC RFFESHVARA NVKHLKILNT PNCALQIVAR LKNNNRQVCI DPKLKWIQEY LEKALN with polyhistidine tag at the C-terminus.
Measure by its ability to chemoattract human THP1 cells using a concentration range of 20-100 ng/mL.
Accession: P48061
Endotoxin: < 0.1 EU per μg protein as determined by LAL test
Lyophilized from a 0.2 µm filtered solution containing 20 mM sodium citrate, 0.1 M NaCl, pH 4.5.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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