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Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. It contributes to leukocyte function, regulates the cytoskeleton, and activates intracellular NADPH oxidase. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9.
The recombinant human S100A8 & S100A9 heterodimer expressed the target gene encoding human S100A8 (Met1-Glu93) with a polyhistidine tag at the C-terminus and human S100A9 (Met1-Pro114) with a flag tag at the C-terminus.
Accession: P05109&P06702
Apparent Molecular Weight: 13&15 kDa, under reducing conditions
Endotoxin < 1 EU/µg
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10% Glycerol, 1 mM TCEP, pH 8.0.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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