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Prostaglandin-D2 Synthase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. It binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. PTGDS possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system.
Recombinant Human Prostaglandin-D2 Synthase (PTGDS) expressed the target gene encoding Ala23-Gln190 with a 6His tag at the C-terminus.
Accession: P41222
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 20-27 KDa, reducing conditions
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
The product is shipped on dry ice packs. Upon receipt, store it immediately at the temperature listed below.
| Form | Solution |
| Storage | Store at ≤ -70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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