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Recombinant Human NT-3 (E.coli)

Cat. No. M15079

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human NT-3 (E.coli) Structure
Synonym:

Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2

Size Price Availability Quantity
10ug USD 330 In stock
50ug USD 980 In stock
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Quality Control & Documentation
  • Purity: >95% , Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Species: Human
Expression system: E.coli
Purity: > 95% as determined by reduced SDS-PAGE
Endotoxin: less than 0.001 ng/ug (0.01 EU/ug)
Storage and stability: Lyophilized proteins should be stored at < -20°C but can be stored at room temperature for up to 3 weeks. The recombinant protein solution can be stored at 4-7℃ for 2-7 days. The isometric solution of the recombinant sample was stable at < -20°C for 3 months.


Bioactivity: Neurotrophic factor-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. NT3 cDNA encodes a precursor protein with 257 amino acid residues and a proprotein containing a signal peptide, which is cleaved to produce an NT3 mature protein with 119 amino acid residues. The amino acid sequence of mature human, mouse and rat NT-3 is identical. Nt-3 selectively promotes differentiation and survival of specific neuronal subsets in the central and peripheral nervous systems.

Chemical Information
Solubility (25°C) It is not recommended to reconstitute to a concentration less than 100μg/ml.
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] D R Safina, et al. Bioorg Khim. [Oligomeric organization of recombinant human neurotrophins expressed in Escherichia coli cells]

[2] Haidi Zhang, et al. Cell. Single processing center models for human Dicer and bacterial RNase III

[3] J O Hui, et al. J Protein Chem. Human neurotrophin-3: a one-step peptide mapping method and complete disulfide characterization of the recombinant protein

[4] A Shintani, et al. Biochem Biophys Res Commun. Monoclonal antibodies against human neurotrophin-3

[5] S Honda, et al. Arch Biochem Biophys. Escherichia coli-derived human interferon-gamma with Cys-Tyr-Cys at the N-terminus is partially N alpha-acylated

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Keywords: Recombinant Human NT-3 (E.coli), Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2 supplier, Cytokines and Growth Factors, inhibitors, activators

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