Free shipping on all orders over $ 500

Recombinant Human Neurolysin Protein (E. coli, His Tag)

Cat. No. M45322

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human Neurolysin Protein (E. coli, His Tag) Structure
Synonym:

NLN

Size Price Availability Quantity
50ug USD 720 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

The recombinant human Neurolysin/NLN consists of 685 amino acids and predicts a molecular mass of 78.7 kDa. A DNA sequence encoding the human NLN (Ser38-Pro704) is expressed with a polyhistidine tag at the N-terminus.

Measured by its ability to cleave a fluorogenic peptide substrate, (7-methoxycoumarin-4-yl)acetyl Pro-Leu-Gly-Pro-D-Lys(2,4-dinitrophenyl)-OH, the specific activity is > 100 pmol/min/μg.


Endotoxin < 1 EU/µg

Apparent Molecular Weight: 67 kDa, reducing conditions

Lyophilized from sterile PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Srinidhi Jayaraman, et al. J Pharmacol Exp Ther. Identification and Characterization of Two Structurally Related Dipeptides that Enhance Catalytic Efficiency of Neurolysin

[2] Vardan T Karamyan. Med Hypotheses. Peptidase neurolysin is an endogenous cerebroprotective mechanism in acute neurodegenerative disorders

[3] M Ursula Norman, et al. Am J Physiol Heart Circ Physiol. Endopeptidases 3.4.24.15 and 24.16 in endothelial cells: potential role in vasoactive peptide metabolism

[4] V Oliveira, et al. Biochemistry. Substrate specificity characterization of recombinant metallo oligo-peptidases thimet oligopeptidase and neurolysin

[5] V Rioli, et al. Biochem Biophys Res Commun. Neuropeptide specificity and inhibition of recombinant isoforms of the endopeptidase 3.4.24.16 family: comparison with the related recombinant endopeptidase 3.4.24.15

Related Cytokines and Growth Factors Products
Recombinant Human HGF (CHO-expressed)

Recombinant human Hepatocyte Growth Factor (rhHGF) , also known as hepatopoietin-A and scatter factor, is a pleiotropic mitogen belonging to the peptidase S1 family (plasminogen subfamily). It is produced by mesenchymal cells and acts on epithelial cells, endothelial cells and haemopoietic progenitor cells.

Recombinant Human RIPK3 Protein (E. coli, N-His)

RIPK3 is a kinase that controls necroptosis and apoptosis. In necroptosis, activated by TNF-α and ZBP1, RIPK3 phosphorylates MLKL, leading to membrane damage. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental models of critical illness. RIPK3 promotes kidney tubular injury via mitochondrial dysfunction. The FAO-dependent RIPK3 mediates pathogenesis of acute lung injury.

Recombinant Influenza B Hemagglutinin/HA Protein (HEK293, C-His)

Recombinant Influenza B Hemagglutinin / HA Protein is a homotrimer that recognizes target cells in vertebrates and does so by binding to salivary acid-containing receptors on these cells. When it binds to the target cell, it causes the host inner membrane to fuse with the viral membrane, thereby facilitating the entry of the viral genome into the target cell.

Recombinant Human FGF-9 (E. coli)

Fibroblast Growth Factor-9 (FGF-9) is a heparin binding growth factor that belongs to the fibroblast growth factor (FGF) family. ED50 < 2.0 ng/ mL, determined by 3T3 cell proliferation assay, corresponding to > 5.0× 105 units/mg.

Recombinant Human CXCL13/BCA-1 (E. coli)

CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml.

  Catalog
Abmole Inhibitor Catalog




Keywords: Recombinant Human Neurolysin Protein (E. coli, His Tag), NLN supplier, Cytokines and Growth Factors, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.