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Recombinant Human NAP-2/CXCL7 (E. coli)

Cat. No. M15027

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human NAP-2/CXCL7 (E. coli) Structure
Synonym:

NAP-2/CXCL7 (E. coli)

Size Price Availability Quantity
10ug USD 345 In stock
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Quality Control & Documentation
  • Purity: >97% , Endotoxin < 1 EU/μg
  • COA
  • MSDS
Biological Activity

Species: Human
Expression system: E. coli
Purity: SDS-PAGE analysis > 97%, HPLC analysis > 97%
Endotoxin: protein content < 1 EU/μg by LAL method
Theoretical molecular weight: 7.6 kDa
Storage and stability: After receiving, the product remains stable at -70°C or -20°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. Avoid repeated freeze-thaw cycles.


Bioactivity: Fully bioactive compared to the standard. Chemotactic bioassay of human peripheral blood neutrophil was used to determine the bioactivity in the concentration range of 1.0-10.0 ng/ mL. Similar to other ELR domains that contain CXC-chemokines, such as IL-8 and GRO proteins, NETP-2 has been shown to bind CXCR-2 and chemotaxis and activate neutrophils. Although CTAP-III, β-TG, and PBP represent amino-terminal extension variants of NETP-2 and share the same CXC chemokine domain, these proteins do not exhibit NETP-2 activity. Recently, it has been shown that the additional amino-terminal residues of CTAP-III mask the critical ELR receptor binding domain exposed to NETP-2, which may account for the lack of activity of NETP-2.

Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Helena M Linge, et al. Antimicrob Agents Chemother. The human CXC chemokine granulocyte chemotactic protein 2 (GCP-2)/CXCL6 possesses membrane-disrupting properties and is antibacterial

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Keywords: Recombinant Human NAP-2/CXCL7 (E. coli), NAP-2/CXCL7 (E. coli) supplier, Cytokines and Growth Factors, inhibitors, activators

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