All AbMole products are for research use only, cannot be used for human consumption.
Mip-1α polymorphism is associated with HIV susceptibility or drug resistance. Recombinant MIP-1α induces dose-dependent suppression of HIV and SIV infection. In response to endogenous and exogenous factors such as interleukin-1 β, interferon -γ, and gram-positive bacterial lipoteichoic acid, monocytes can secrete large amounts of MIP-1α. Mip-1α enhances the adhesion of T lymphocytes, monocytes, and neutrophils to vascular cell adhesion molecule 1. In addition, miP-1α accelerates tissue repair by chemically attracting macrophages during trauma.
Recombinant Human MIP-1α/CCL3 expressed the target gene encoding Ser24-Ala92.
ED50 < 100.0 ng/ mL, calcium flux was measured using CHO/Gα15 cells expressing CCR5.
Accession: P10147
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 12 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[4] C Blanpain, et al. Blood. CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist
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Products are for research use only. Not for human use. We do not sell to patients.
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