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Recombinant Human KRAS (G12D, E. coli, His)

Cat. No. M11234

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human KRAS (G12D, E. coli, His) Structure
Synonym:

Recombinant Human KRAS G12D (E. coli, His)

Size Price Availability Quantity
50ug USD 440 In stock
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Quality Control & Documentation
  • Purity: >90%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
Biological Activity

The KRAS gene provides instructions for making a protein called K-Ras, part of the RAS/MAPK pathway. The K-Ras protein is a GTPase, which means it converts a molecule called GTP into another molecule called GDP. In this way the K-Ras protein acts like a switch that is turned on and off by the GTP and GDP molecules. 


Accession #: P01116-2 

Molecular Weight: 23.8 kDa 

Endotoxin: ≤ 1 EU/μg 

Lyophilized from a 0.2 μm filtered solution in PBS.

Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
Storage Stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
References

[1] Yongde Luo, et al. Gastroenterology. Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet

[2] Callum P Rakhit, et al. Dis Model Mech. Early detection of pre-malignant lesions in a KRAS G12D-driven mouse lung cancer model by monitoring circulating free DNA

[3] Shanmin Zhao, et al. Cell Physiol Biochem. KRAS (G12D) cooperates with AML1/ETO to initiate a mouse model mimicking human acute myeloid leukemia

[4] Victoria A Appleman, et al. Mol Cancer Res. KRAS(G12D)- and BRAF(V600E)-induced transformation of murine pancreatic epithelial cells requires MEK/ERK-stimulated IGF1R signaling

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Keywords: Recombinant Human KRAS (G12D, E. coli, His), Recombinant Human KRAS G12D (E. coli, His) supplier, Cytokines and Growth Factors, inhibitors, activators

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