All AbMole products are for research use only, cannot be used for human consumption.
KIAA11, also known as p15(PAF), is a proliferating cell nuclear antigen-associated factor that interacts with proliferating cell nuclear antigen(PCNA). KIAA11 is localized primarily in the nucleus. It shares the conserved PCNA binding motif with several other PCNA binding proteins including CDK inhibitor p21. KIAA11 is involved in cell proliferation and plays a role in early tumor recurrence (ETR), and prognosis of hepatocellular carcinoma (HCC). KIAA11 is expressed predominantly in the liver, pancreas, and placenta.
The recombinant human PAF consisting of 126 amino acids and has a calculated molecular mass of 13.8 KDa.
A DNA sequence encoding the human PAF isoform 1 (Met 1-Glu 111) was expressed, with a polyhistide tag at the N-terminus.
Lyophilized from sterile PBS, pH 7.5.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for up to one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[4] Zeina Kais et al. Mol Cancer Res. KIAA0101 interacts with BRCA1 and regulates centrosome number
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Products are for research use only. Not for human use. We do not sell to patients.
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