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Recombinant Human KGF (E.coli)

Cat. No. M15069

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human KGF (E.coli) Structure
Synonym:

Fibroblast growth factor 7; FGF-7

Size Price Availability Quantity
10ug USD 255 In stock
50ug USD 700 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/ug
  • COA
  • MSDS
Biological Activity

Recombinant Human KGF (FGF7) is a secreted protein mainly located in epithelial cells and belongs to the heparin binding growth factor family. FGF family members have a wide range of mitosis and cell survival activities and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a powerful epithelial cell-specific growth factor with mitotic activity mainly in keratinocytes rather than fibroblasts and endothelial cells. This may be the main paracrine effect of normal epithelial cell proliferation.

Recombinant Human Fibroblast Growth Factor 7/Keratinocyte Growth Factor expressed the target gene encoding Cys32-Thr194.


Accession # : P21781

Expression system: E.coli

Endotoxin < 1 EU/ug

Lyophilized from a 0.2 μm filtered solution of 20mM Tris,1mM EDTA,5% Trehalose, 0.02% Tween 80, pH 8.0.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Young Su Kim, et al. Microb Cell Fact. Effective production of human growth factors in Escherichia coli by fusing with small protein 6HFh8

[2] Mansoureh Shahbazi Dastjerdeh, et al. Comput Biol Chem. In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli

[3] Jason C Gardner, et al. Am J Physiol Lung Cell Mol Physiol. Keratinocyte growth factor supports pulmonary innate immune defense through maintenance of alveolar antimicrobial protein levels and macrophage function

[4] Xiaoping Wu, et al. Appl Microbiol Biotechnol. Large-scale production of biologically active human keratinocyte growth factor-2

[5] Jun-Hyeog Jang. Biotechnol Lett. Stimulation of human hair growth by the recombinant human keratinocyte growth factor-2 (KGF-2)

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Keywords: Recombinant Human KGF (E.coli), Fibroblast growth factor 7; FGF-7 supplier, Cytokines and Growth Factors, inhibitors, activators

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