All AbMole products are for research use only, cannot be used for human consumption.
The role of Recombinant Human IL-4 Protein (CHO) in the induction of monocytes into DCs is to inhibit the overgrowth of macrophages, thereby directing monocyte differentiation toward DCs. Also, IL-4 has the ability to reduce cell surface expression of CD14 molecules, an important marker for the differentiation of monocytes into DCs. The combined effect of GM-CSF and IL-4 can lead to targeted differentiation of monocytes into immature DCs, which have a strong capacity for antigen uptake and processing, but a weak capacity for antigen presentation.
DNA sequence encoding human IL-4 ( GenBank: AAH70123.1 H25-S153 ) expressed with an Fc tag at the C- terminus.
Measured by the cell proliferation assay with TF-1 cells, the ED50 is ≤0.5 ng/mL.
Endotoxin <0.1 EU/μg
Eur J Med Res. 2025 Apr 11;30(1):271.
M2 macrophage-derived exosomes reverse TGF-β1-induced epithelial mesenchymal transformation in BEAS-2B cells via the TGF-βRI/Smad2/3 signaling pathway
Recombinant Human IL-4 Protein (CHO, C-Fc) purchased from AbMole
Patent. CN119138406B 2025 Mar 07; .
Patent. CN119138406B
Recombinant Human IL-4 Protein (CHO, C-Fc) purchased from AbMole
Patent. CN119138406A 2024 Dec 17.
Patent. CN119138406A
Recombinant Human IL-4 Protein (CHO, C-Fc) purchased from AbMole
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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