All AbMole products are for research use only, cannot be used for human consumption.
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation.
Recombinant Human Interleukin-25 expressed the target gene encoding Tyr33-Gly177 with a polyhistidine tag at the C-terminus.
Measure by its ability to induce IL-8 secretion in human PBMCs, the ED50 for this effect is <5 ng/mL.
Measure by its ability to induce CXCL1 secretion in HT29 cells, the ED50 for this effect is <1 ng/mL.
Accession: Q9H293
Endotoxin < 0.1 EU/µg
Apparent Molecular Weight: 19 KDa, reducing conditions
Lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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| Recombinant Human FGF-9 (E. coli)
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| Recombinant Human CXCL13/BCA-1 (E. coli)
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Products are for research use only. Not for human use. We do not sell to patients.
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