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Insulin-like growth factor I (IGF1) binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions.
Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is 20-100 ng/ml.
| Molecular Weight | 7645.68 |
| Formula | C331H512N94O101S7 |
| CAS Number | 68562-41-4 |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration of 100μg/ml |
| Storage | Stored at ≤ -20°C, stable for one year after receipt |
[3] George M Bright. Growth Horm IGF Res. Recombinant IGF-I: Past, present and future
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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