All AbMole products are for research use only, cannot be used for human consumption.
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and differentiation. It is heterodimer with EGFR, ERBB3 and ERBB4. HER2 associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. It implicated in transcriptional activation of CDKN1A and the function of the protein involves STAT3 and SRC.
Recombinant Human epidermal growth factor receptor 2 (HER2) expressed the target gene encoding Thr23-Thr652 with a 6His tag at the C-terminus.
Loaded Anti-Human HER2 mAb on Protein A Biosensor, can bind Human HER2-His with an affinity constant of 1.36 nM as determined in BLI assay.
Accession: P04626
Apparent Molecular Weight: 90-120 KDa, reducing conditions
Endotoxin < 1 EU/µg
Lyophilized from a 0.2 μm filtered solution of 20mM Citrate, 8% Sucrose, 0.05% Tween 80, pH 4.5.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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