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Recombinant Human Granulocyte Colony Stimulating Factor (CHO)

Cat. No. M10313

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human Granulocyte Colony Stimulating Factor (CHO) Structure
Synonym:

Recombinant Human G-CSF (CHO)

Size Price Availability Quantity
10ug USD 190 In stock
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Quality Control & Documentation
  • Purity: >97%, Endotoxin <0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Human Granulocyte Colony Stimulating Factor (G-CSF) is a pleiotropic cytokine, mainly produced by monocytes and macrophages upon activation by endotoxin, TNF-α and IFN-γ. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. G-CSF is cytokine that acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. In addition it may function in some adhesion or recognition events at the cell surface. Human G-CSF is 73 % identical at the amino acid level to murine G-CSF and the two proteins show species cross-reactivity.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Athanasia D Panopoulos, et al. Cytokine. Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis

[2] G D Demetri, et al. Blood. Granulocyte colony-stimulating factor and its receptor

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Keywords: Recombinant Human Granulocyte Colony Stimulating Factor (CHO), Recombinant Human G-CSF (CHO) supplier, Cytokines and Growth Factors, inhibitors, activators

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