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Species: Human
Expression system: Human Cells
Purity: > 95% as determined by reduced SDS-PAGE
Endotoxin: LAL test measured less than 0.1 ng/µg (1eu /µg)
Molecular weight: 36.7KDa
Storage and stability: Freeze-dried protein should be stored at < -20℃, but stable at room temperature for 3 weeks. The recombinant protein solution can be stored at 4-7℃ for 2-7 days. The bisector of the recombinant sample was stable at < -20°C for 3 months.
Bioactivity: Galectin-9 is a cytoplasmic protein containing two galectin-domains. Galactin-9 is an S-type lectin that is overexpressed in Hodgkin's disease tissues. Galactosidine -9 binds galactoside and has a high affinity for Forssman five sugars. Galactin-9 plays a role in thymocyte-epithelial interactions, is relevant to thymus biology, and inhibits cell proliferation. Galectin-9, a ligand of HAVCR2/TIM3, induces the death of T-helper type 1 lymphocytes (Th1). In addition, Galectin-9 inhibits tumor cell metastasis by interfering with CD44, VCAM-1, Integrin α4β1 and other factors.
| Solubility (25°C) | It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Valerie R Wiersma, et al. Med Res Rev. Therapeutic potential of Galectin-9 in human disease
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Products are for research use only. Not for human use. We do not sell to patients.
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