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Fms-like Tyrosine Kinase 3 Ligand (FLT3L) is a hematopoietic four helical bundle cytokine. Flt‑3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts. It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 receptor.
Recombinant Human Fms-like Tyrosine Kinase 3 Ligand expressed the target gene encoding Thr27-Pro184 with a 6His tag at the C-terminus.
Immobilized Human FLT3L (C-6His) at 5 μg/ml (100 μl/well) can bind Human FLT3, the EC50 of Human FLT3 is not higher than 10 ng/ml.
Accession: P49771
Endotoxin < 0.01 EU/µg
Apparent Molecular Weight: 24-32 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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