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FLT3-ligand (HEK293) is a growth factor that regulates the proliferation of early hematopoietic cells. FLT 3-ligand binds to cells expressing FLT 3, the tyrosine kinase receptor. FLT3-ligand itself does not stimulate the proliferation of early hematopoietic cells, but cooperates with other CSFs and interleukins to induce growth and differentiation.
Recombinant human Flt3-Ligand contains 161 amino acids and has a predicted molecular weight of 18.4kd.
ED50 stimulates the proliferation activity of human AML5 cells in a dose-dependent manner to be ≤1.0ng/ml, and the corresponding specific activity is ≥1×106 IU/mg.
Expression host is Human HEK293 cells
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| Related Cytokines and Growth Factors Products |
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| Recombinant Human CD48/SLAMF2 (HEK293,C-Fc-6His)
Recombinant human CD48/SLAMF2 protein plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma. |
| Recombinant Human IFNγ (CHO)
Human Interferon gamma (hIFN-γ) (CHO) is a dimerized soluble cytokine that is the only member of the type II class of interferons. |
| Recombinant Human EPO Protein (CHO)
Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. |
| Recombinant Human GM-CSF (HEK293, C-His)
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor is a hematopoietic growth factor and immune modulator. |
| Recombinant Human IL-1α Protein (E. coli)
Interleukin 1 (IL-1) is a peptide with a molecular mass of 17 kd and two isoforms, IL-1α and IL-1β. IL-1ɑ consists of 159 amino acids. Measured by its ability to induce interferon γ secretion from human natural killer lymphoma NK-92 cells, the ED50 of this effect is ≤100 ng/mL. |
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