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Recombinant Human EGF Protein (E.coli)

Cat. No. M40746

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human EGF Protein (E.coli) Structure
Synonym:

Epidermal Growth Factor; Urogastrone

Size Price Availability Quantity
10ug USD 85 In stock
50ug USD 130 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.01 EU/μg
  • COA
  • MSDS
Biological Activity

Epidermal growth factor (EGF) is a small mitogenic protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. It shows both strong sequential and functional homology with human type-alpha transforming growth factor (hTGF alpha), which is a competitor for EGF receptor sites.

Recombinant Human Epidermal Growth Factor expressed the target gene encoding Asn971-Arg1023.

Measured in a cell proliferation assay using BALB/c 3T3 cells, the ED50 is 60-450 pg/ml.


Accession: P01133

Apparent Molecular Weight: 11 KDa, reducing conditions

Endotoxin < 0.01 EU/µg

Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 200mM NaCl, pH 8.0.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Enjie Li et al. Elife. METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis

[2] Misako Nagasaka et al. Trends Cancer. NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis

[3] Xiaoling Qiang et al. Int J Mol Med. Expression and characterization of recombinant human milk fat globule-EGF factor VIII

[4] Y Stenberg et al. Eur J Biochem. Characterization of recombinant epidermal growth factor (EGF)-like modules from vitamin-K-dependent protein S expressed in Spodoptera cells--the cofactor activity depends on the N-terminal EGF module in human protein S

[5] B Mroczkowski et al. Mol Cell Biol. Recombinant human epidermal growth factor precursor is a glycosylated membrane protein with biological activity

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Keywords: Recombinant Human EGF Protein (E.coli), Epidermal Growth Factor; Urogastrone supplier, Cytokines and Growth Factors, inhibitors, activators

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