All AbMole products are for research use only, cannot be used for human consumption.
Species: Human
Expression system: HEK 293
Purity: SDS-PAGE, > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: 65~ 75kDa, reduced on SDS-PAGE
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.
Bioactivity: 5.0 μg/ mL (100 μ L/well) immobilized human IL-2 can bind to CD25/IL-2Rα, hFc and human IL-2Rα. Activation T cells, regulatory T cells (Tregs) and NK cells expressed CD25 at high levels, and the expression of high-affinity IL-2Rα was mainly confined to these cell populations. The il-2R α signaling pathway mediates a variety of biological processes in various cell populations, such as proliferation and differentiation of B cells and NK cells. A soluble form of IL-2Rα (IL-2Rα) is present in serum with increased expression on cells. The function of soluble IL-2Rα is unclear. Increased il-2R α levels in biological fluids have been reported to be associated with increased T and B cell activation and immune system activation. Serum il-2R α concentrations are elevated in many inflammatory processes and in some leukemias and lymphomas.
| Solubility (25°C) | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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