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Recombinant Human Adiponectin (CHO)

Cat. No. M15042

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human Adiponectin (CHO) Structure
Synonym:

Acrp-30; GBP-28; Apm-1

Size Price Availability Quantity
10ug USD 188 In stock
50ug USD 448 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Adiponectin antagonizes THF by negatively regulating THF expression. Adiponectin also inhibits endothelial NF-Kappa-B signaling through a camp-dependent pathway. Adiponectin can form low molecular weight complex (LMW), medium molecular weight complex (MMW) and high molecular weight complex (HMW). They bind to various growth factors, such as HBEGF, PDGFB and FGF2, and play a role in cell growth, angiogenesis and tissue remodeling.

Measured by M1 cell growth inhibition assay, the ED50 is < 20.0 μg/mL.


Accession # Q15848

Endotoxin < 0.2 EU/μg

Apparent Molecular Weight: 25~28 kDa, reducing conditions

Lyophilized after extensive dialysis against PBS.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Zhongjie Fu, et al. EMBO Mol Med. Photoreceptor glucose metabolism determines normal retinal vascular growth

[2] Yoshiki Terashima, et al. J Orthop Surg Res. Expression of adiponectin receptors in human and rat intervertebral disc cells and changes in receptor expression during disc degeneration using a rat tail temporary static compression model

[3] Jun Wada. Expert Opin Investig Drugs. Vaspin: a novel serpin with insulin-sensitizing effects

[4] Ayanthi A Richards, et al. Mol Endocrinol. Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: evidence for regulation of multimerization by alterations in posttranslational modifications

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Keywords: Recombinant Human Adiponectin (CHO), Acrp-30; GBP-28; Apm-1 supplier, Cytokines and Growth Factors, inhibitors, activators

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