All AbMole products are for research use only, cannot be used for human consumption.
Reboxetine mesylate is a potent, selective, and specific norepinephrine reuptake inhibitor. Reboxetine has weak affinity (Ki > 1,000 nmol/L) for muscarinic, histaminergic H1, adrenergic alpha1, and dopaminergic D2 receptors. Repeated administration of reboxetine (5.6 mg/kg) decreased nicotine self-administration and sucrose-maintained responding across the 14 sessions, suggesting that tolerance did not develop to these effects of reboxetine. Additionally, reboxetine did not alter baseline locomotor activity, indicating that the decrease in operant responding for nicotine and sucrose was not the result of a nonspecific decrease in activity. The reboxetine-induced decrease in nicotine self-administration and sucrose-maintained responding may be the result of inhibition of norepinephrine transporters and/or neuronal nicotinic receptor function.
| Molecular Weight | 409.5 |
| Formula | C19H23NO3.CH3SO3H |
| CAS Number | 98769-84-7 |
| Solubility (25°C) | DMSO 75 mg/mL Water 35 mg/mL |
| Storage | 2-8°C |
| Related Adrenergic Receptor Products |
|---|
| Tamsulosin hydrochloride
Tamsulosin is a new, highly selective α1A-adrenoceptor antagonist. |
| Mirabegron
Mirabegron (YM178) is a potent and selective β(3)-adrenoceptor agonist with EC50 of 22.4 nM. |
| Detomidine hydrochloride
Detomidine hydrochloride is a nonnarcotic, synthetic alpha-2 adrenoreceptor agonist. |
| (R)-(+)-Atenolol
(R)-(+)-Atenolol binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. |
| Acebutolol hydrochloride
Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
