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Raxatrigine hydrochloride

Cat. No. M10470

All AbMole products are for research use only, cannot be used for human consumption.

Raxatrigine hydrochloride Structure
Synonym:

GSK1014802; CNV-1014802 HCl

Size Price Availability Quantity
1mg USD 60 In stock
5mg USD 150 In stock
10mg USD 240 In stock
25mg USD 525 In stock
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Quality Control & Documentation
Biological Activity

Raxatrigine hydrochloride (GSK-1014802 hydrochloride) is a selective, small-molecule, state-dependent Nav1.7 voltage-gated sodium channel blocker.

Chemical Information
Molecular Weight 350.82
Formula C18H20ClFN2O2
CAS Number 934240-31-0
Solubility (25°C) DMSO 30 mg/mL
Water 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jennifer R Deuis, et al. Toxins (Basel). Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain

[2] Sharan K Bagal, et al. Bioorg Med Chem Lett. Recent progress in sodium channel modulators for pain

[3] Charles H Large, et al. J Pharmacol Exp Ther. The efficacy of sodium channel blockers to prevent phencyclidine-induced cognitive dysfunction in the rat: potential for novel treatments for schizophrenia

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Keywords: Raxatrigine hydrochloride, GSK1014802; CNV-1014802 HCl supplier, Sodium Channel, inhibitors, activators

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